Antimicrobial Properties of Strychnos phaeotricha (Loganiaceae) Liana Bark Secondary Metabolites at the Interface of Nanosilver Particles and Nanoencapsulation by Chitosan Transport Vehicles

In this study, Strychnos phaeotricha liana bark extract was used as a metabolite container both on the surface of metallic nanosilver and encapsulated by chitosan polymer. The plant able to reduce Ag+ into Ag0 efficiently, encapsulation rate determined. synthesized nanoderivatives were characterized using ultraviolet-visible spectrophotometry (UV-Vis), Fourier transform infrared (FTIR) spectroscopy, powder X-ray diffraction (PXRD), scanning electron microscopy (SEM), energy dispersive (EDX) spectroscopy. These methods allowed for determination grain size, elemental mapping, form, presence secondary metabolites at interface silver. Antimicrobial properties oral acute toxicity profile generated assessed. Overall, results show plasmon resonance bands 380–550 nm in range spherical 13.5 diameter size. hybrid exhibited significant antimicrobial activity against Salmonella spp, Echerichia coli, Candida spp. Both grains nanocapsules found be nontoxic tested doses are potential models prevent microbial resistance.